Uzziah, with a censer in his hand to offer incense, was enraged. But while he raged against the priests in their presence in the house of the LORD before the altar of incense, leprosy broke out on his forehead.
Here is the only blot we find on the name of king Uzziah, and it is such a one as lies not on any other of the kings. Whoredom, murder, oppression, persecution, and especially idolatry, gave characters to the bad kings and some of them blemishes to the good ones, David himself not excepted, witness the matter of Uriah.
Commenting on 2 Chronicles 26:16-23
And Uzziah the king was a leper unto the day of his death, and dwelt in a several house, being a leper,.... See Gill on Kg2 15:5, for he was cut off from the house of the Lord; not, suffered to enter into that, because of his uncleanness: and Jotham his son was over the king's house, judging the people of the land; see Kg2 15:5.
2Ch 26:17-20 The king’s purpose was consequently opposed by the high priest Azariah and eighty priests, valiant men, who had the courage to represent to him that to burn incense to the Lord did not appertain to the king, but only to the sanctified Aaronite priests; but the king, with the censer in his hand, was angry, and the leprosy suddenly broke out upon his forehead.
Commenting on 2 Chronicles 26:17-20