The hand of the Lord was with them, and a great number of people believed and turned to the Lord.
21. The hand of the Lord was. Luke proveth by the success that the gospel was offered unto the Gentiles also by the brethren of Cyprus and Cyrene not rashly nor unadvisedly, because their labor was fruitful and profitable. But such increase should never have followed, unless God had commanded and favored. Therefore, it followeth that it pleased God that the Gentiles should be called.
We have here an account of the planting and watering of a church at Antioch, the chief city of Syria, reckoned afterwards the third most considerable city of the empire, only Rome and Alexandria being preferred before it, next to whose patriarch that of Antioch took place. It stood where Hamath or Riblah did, which we read of in the Old Testament.
Commenting on Acts 11:19-26
Then tidings of these things,.... Of the spread of the Gospel in several parts, and the success of it in the conversion of sinners, especially at Antioch: came unto the ears of the church which was in Jerusalem; these tidings were brought to the apostles and brethren there, by messengers which the ministers of the word sent unto them to let them know what success...