Isaiah
Isaiah 49:4BSB·traditional attribution

But I said, “I have labored in vain, I have spent My strength in futility and vanity; yet My vindication is with the LORD, and My reward is with My God.”

Matthew Henry Presbyterian @wholebiblehenry

Here, I. An auditory is summoned together and attention demanded. The sermon in the foregoing chapter was directed to the house of Jacob and the people of Israel, Isa 49:1, Isa 49:12. But this is directed to the isles (that is, the Gentiles, for they are called the isles of the Gentiles, Gen 10:5) and to the people from far, that were strangers to the...

Commenting on Isaiah 49:1-6

John Gill Reformed Baptist @doctorgill

Then I said,.... The Messiah said, by way of objection, in a view of what treatment he should meet with, or when entered on his work, and which he found by experience, what follows: I have laboured in vain; this is not to be understood of the travail of his soul, or of his sufferings and death, which were not in vain, but issued in...

Jamieson-Fausset-Brown Reformed @jfbcommentary

I--Messiah. in vain--comparatively in the case of the greater number of His own countrymen. "He came unto His own, and His own received Him not" (Isa 53:1-3; Luk 19:14; Joh 1:11; Joh 7:5). Only a hundred twenty disciples met after His personal ministry was ended (Act 1:15). yet . . . my judgment . . .