Isaiah 7:8 (BSB)

For the head of Aram is Damascus, and the head of Damascus is Rezin. Within sixty-five years Ephraim will be shattered as a people.

From Isaiah 7. Also in the ESV.

Commentary on Isaiah 7:8

• John Calvin (Reformed), Calvin's Commentaries on Isaiah 7:8: 8. For the head of Syria is Damascus. As if he had said, “Those two kings shall have their limits, such as they have them now. They aspire to thy kingdom; but I have set bounds to them which they shall not pass.” Damascus was the metropolis of Syria, as Paris is of France.
• Matthew Henry (Presbyterian), Matthew Henry's Complete Commentary on Isaiah 7:1-9: The prophet Isaiah had his commission renewed in the year that king Uzziah died, Isa 6:1. Jotham his son reigned, and reigned well, sixteen years. All that time, no doubt, Isaiah prophesied as he was commanded, and yet we have not in this book any of his prophecies dated in the reign of Jotham; but this, which is put first, was in the days of Ahaz the son of Jotham.
• John Gill (Reformed Baptist), Exposition of the Old and New Testaments on Isaiah 7:8: For the head of Syria is Damascus,.... Damascus was the metropolis of Syria, the chief city in it, where the king had his palace, and kept his court; of which See Gill on Gen 15:2, Act 9:2, and the head of Damascus is Rezin; he was king of it, as of all Syria; the meaning is, that Syria, of which Damascus was the principal city...
• Jamieson-Fausset-Brown (Reformed), Commentary Critical and Explanatory on the Whole Bible on Isaiah 7:8: head--that is, in both Syria and Israel the capital shall remain as it is; they shall not conquer Judah, but each shall possess only his own dominions. threescore and five . . . not a people--As these words break the symmetry of the parallelism in this verse, either they ought to be placed after "Remaliah's son," in Isa 7:9, or else they refer to some...