Oh, that a man might plead with God as he pleads with his neighbor!
Job's condition was very deplorable; but had he nothing to support him, nothing to comfort him? Yes, and he here tells us what it was. I. He had the testimony of his conscience for him that he had walked uprightly, and had never allowed himself in any gross sin.
Commenting on Job 16:17-22
When a few years are come,.... As the years of man's life are but few at most, and Job's years, which were yet to come, still fewer in his apprehension; or "years of number" (m), that are numbered by God, fixed and determined by him, Job 14:5; or being few are easily numbered: then I shall go the way whence I shall not return; that...
one--rather, "He" (God). "Oh, that He would plead for a man (namely, me) against God." Job quaintly says, "God must support me against God; for He makes me to suffer, and He alone knows me to be innocent" [UMBREIT]. So God helped Jacob in wrestling against Himself (compare Job 23:6; Gen 32:25). God in Jesus Christ does plead with God for man (Rom 8:26-27).