Here is a call for wisdom: Let the one who has insight calculate the number of the beast, for it is the number of a man, and that number is 666.
Those who think the first beast signifies Rome pagan by this second beast would understand Rome papal, which promotes idolatry and tyranny, but in a more soft and lamb-like manner: those that understand the first beast of the secular power of the papacy take the second to intend its spiritual and ecclesiastical powers, which act under the disguise of religion and charity to the souls of men. Here observe, I.
Commenting on Revelation 13:11-18
Verse 18. Here is wisdom. That is, in what is stated respecting the name and the number of the name of the beast. The idea is, either that there would be need of peculiar sagacity in determining what the "number" of the "beast" or of his "name" was, or that peculiar "wisdom" was shown by the fact that the number could be thus expressed.
wisdom--the armory against the second beast, as patience and faith against the first. Spiritual wisdom is needed to solve the mystery of iniquity, so as not to be beguiled by it. count . . . for--The "for" implies the possibility of our calculating or counting the beast's number. the number of a man--that is, counted as men generally count. So the phrase is used in Rev 21:17.