The hand of the LORD was heavy against the people of Ashdod, and he terrified and afflicted them with tumors, both Ashdod and its territory.
The downfall of Dagon (if the people had made a good use of it, and had been brought by it to repent of their idolatries and to humble themselves before the God of Israel and seek his face) might have prevented the vengeance which God here proceeds to take upon them for the indignities done to his ark, and their obstinate adherence to their idol...
Commenting on 1 Samuel 5:6-12
But the hand of the Lord was heavy on them of Ashdod,.... Not only on their idol, but on themselves; it had crushed him to pieces, and now it fell heavy on them to their destruction: and he destroyed them; either by the disease after mentioned they were smitten with, or rather with some other, since that seems not to be mortal, though painful; it...
THE PHILISTINES ARE SMITTEN WITH EMERODS. (Sa1 5:6-12) the hand of the Lord was heavy upon them of Ashdod--The presumption of the Ashdodites was punished by a severe judgment that overtook them in the form of a pestilence. smote them with emerods--bleeding piles, hemorrhoids (Psa 78:66), in a very aggravated form.