Matthew
Matthew 12:48ESV·traditional attribution

But he replied to the man who told him, “Who is my mother, and who are my brothers?”

John Calvin Reformed @genevareformer

Matthew 12:48. Who is my mother? These words were unquestionably intended to reprove Mary’s eagerness, and she certainly acted improperly in attempting to interrupt the progress of his discourse. “Et de faict, c’estoit mal avise a elle de vouloir ainsi rompre son propos, lors qu’il enseignoit;” — “and in fact, it was foolish in her to wish to break off his discourse in this manner...

Matthew Henry Presbyterian @wholebiblehenry

Many excellent, useful sayings came from the mouth of our Lord Jesus upon particular occasions; even his digressions were instructive, as well as his set discourses: as here, Observe, I. How Christ was interrupted in his preaching by his mother and his brethren, that stood without, desiring to speak with him (Mat 12:40, Mat 12:47); which desire of theirs was conveyed to him through the crowd.

Commenting on Matthew 12:46-50

Albert Barnes Presbyterian @notesbybarnes

Verse 48. Who is my mother? etc. There was no want of affection or respect in Jesus towards his mother, as is proved by his whole life. See especially . This question was asked merely to fix the attention of the hearers, and to prepare them for the answer; that is, to show them who sustained towards him the nearest and most tender relation.